Neutrophils

Neutrophils are granulocytes because they have densely staining granules in their cytoplasm. Because of their oddly shaped nuclei they are also called polymorphonuclear leukocytes.

There are three types of granulocytes which are distinguished by the different staining properties of the
granules:
  • neutrophils
  • eosinophils
  • basophils

Neutrophils

Every day the bone marrow produces millions of new neutrophils. They are mainly involved in the initial phase of an inflammatory response. Neutrophils are recruited into the inflamed tissue in large numbers during an inflammation. Neutrophils are also known as inflammatory cells. Neutrophils have surface receptors for common bacterial constituents and for complement which makes them principal cells that engulf and destroy the invading microorganisms.

Macrophages in tissues when when challenged are triggered to release chemokines which direct the migration of neutrophils to the site of infection. TH17 cells produce distinct cytokines that help to promote responses rich in the recruitment of neutrophils and which are effective in dealing with extracellular bacteria and fungi.


Neutrophils simplified

"The bravest warrior is the Neutrophil. It is the first one to go to the battlefield. They gobble up their enemies!"

Neutrophil

Immune system has 2 arms - Innate and Adaptive

Immune system has 2 arms: Innate and Adaptive

Adaptive:
It comprimises of
  • Lymphocytes
  • Antigen presenting cells

Innate:
Bodys first line of defence includes four main types of defensive barriers which are
  • Physical or Anatomical barrier
  • Physiological  barrier
  • Phagocytic barrier
  • Inflamatory barrier

Welcome


IfuM: Why I started this blog?

I have been thinking of blogging information about immunology in a creative way since last year. So, today I finally decided that I am going to do it.

Immunology has been my favorite subject since my second year in graduate college while I was studying microbiology. I love teaching my friends immunology and I through this blog I will be sharing my knowledge and creativity in teaching immunology to the world.

I will be referring basic books of immunology and a few creative articles on the internet for this blog. And the illustrations made on this blog will be made by me.

I will be taking help of my sister and a few friends in making this blog interesting and a fun way to learn.

I have not merged this blog with http://microbiologyme.blogspot.in/ because I feel immunology is a vast subject and it needs its own blog place.

-IfuM