Interleukin-10 (IL-10) mnemonic

Interleukin-10 (IL-10) mnemonic

Interleukin-10 (IL-10):

• It is secreted by regulatory T cells (Treg) in order to inhibit inflammation preventing unwanted immune responses.
• It is also secreted by Th2 cells to suppress Th1 cells and cell mediated immunity; and to induce humoral immunity.
• IL-10 inhibits cytokine release from macrophages, which is why, it is also known as cytokine synthesis inhibitory factor.
• Interesting fact: Beekeepers exposed to repeated stings are often naturally protected from severe allergic reactions such as anaphylaxis through a mechanism that involves IL-10-secreting T cells.

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